Posts

Plastics Inside the Prostate:

Image
Microplastics found in 90% of prostate cancer tumors, study reveals | ScienceDaily What the Latest Research Tells Us About Microplastics and Prostate Cancer A growing body of evidence links tiny plastic particles found inside human tumors to potential cancer risk — but scientists urge caution about overstating a still-early finding. February 28, 2026 Bottom Line Up Front (BLUF) Two independent research teams — one at NYU Langone Health (February 2026) and one at Peking University (September 2024) — have detected microplastics inside prostate tumors at concentrations roughly 1.5 to 2.5 times higher than in adjacent noncancerous prostate tissue. Laboratory research from the Peking University group also shows that polystyrene microplastics can directly stimulate human prostate cancer cells to multiply. These are striking findings, but both research teams urge the same caution: the studies are small, no one has yet proven that microplastics cause prostate ...
Post a Comment
Read more

Iron Metabolism as a Therapeutic Vulnerability in Stem Cell-Like Castration-Resistant Prostate Cancer | bioRxiv

Image
Iron Metabolism as a Therapeutic Vulnerability in Stem Cell-Like Castration-Resistant Prostate Cancer | bioRxiv Iron: The Hidden Fuel Driving a Stubborn Subtype of Castration-Resistant Prostate Cancer — And a New Way to Turn It Against the Tumor Researchers discover that "stem cell-like" CRPC cells depend on iron to survive — and that disrupting iron balance triggers a lethal form of cell death in those cells while leaving others largely untouched. BLUF — Bottom Line Up Front A new laboratory study published in February 2026 from the University of Bern (Switzerland) and McGill University (Canada) has identified a potentially exploitable weakness in one of the most treatment-resistant subtypes of castration-resistant prostate cancer (CRPC). The "stem cell-like" subtype (CRPC-SCL), which accounts for roughly 25% of CRPC cases and resists standard hormone therapy, is uniquely dependent on iron. Cells in this subtype accumulate excess iron...
Post a Comment
Read more

Hidden Metastases Revealed:

Image
PSMA-PET imaging in prostate cancer patients with high-risk biochemical recurrence: implications from an “EMBARK-Like” cohort | Prostate Cancer and Prostatic Diseases How PSMA-PET Scanning Is Rewriting the Rules for Men with Recurring Prostate Cancer A new study — and a landmark trial — are forcing doctors to rethink who is really "non-metastatic" Bottom Line Up Front (BLUF) When prostate cancer returns after surgery or radiation and PSA is rising fast, doctors have traditionally called it "non-metastatic" if a standard CT scan and bone scan showed nothing. A major new study published in February 2026 shows that nearly half of those high-risk patients actually do have metastatic disease — the cancer has already spread — but only the newer PSMA-PET scan can find it. Separately, the landmark EMBARK trial has now demonstrated that intensifying treatment with a combination of enzalutamide (Xtandi) plus standard hormone therapy not only delay...
Post a Comment
Read more