Informed Prostate Cancer Patient Support

The Critical Interplay of CAF Plasticity and Resistance in Prostate Cancer | Cancer Research | American Association for Cancer Research

Nanomechanical‐based classification of prostate tumor using atomic force microscopy - Zeng - The Prostate - Wiley Online Library

Development and internal validation of a nomogram predicting significant prostate cancer: Is it clinically applicable in low prevalent prostate cancer countries? A multicenter study - Arafa - The Prostate - Wiley Online Library

[2309.06268] ssVERDICT: Self-Supervised VERDICT-MRI for Enhanced Prostate Tumour Characterisation

For Some Prostate Cancer Patients, PSMA PET May Be Better for Initial Staging of Disease | UCSF Radiology

Prognostic impact of serum testosterone in metastatic hormon... : Current Opinion in Urology

Comparative analysis of robot-assisted simple prostatectomy: the HUGO™ RAS system versus the DaVinci® Xi system | Prostate Cancer and Prostatic Diseases

The expression of PKM1 and PKM2 in developing, benign, and cancerous prostatic tissues | bioRxiv

Cureus | Cutaneous Metastases in Progressive Prostate Adenocarcinoma: A Case Report and Literature Review | Article

Interim toxicity analysis from the randomised HERMES trial of 2- and 5-fraction MRI-guided adaptive prostate radiotherapy - ScienceDirect

Radiotherapy doses for prostate cancer could be cut by three-quarters, trial finds | Prostate cancer | The Guardian

Genomic evolution of SARS-CoV-2 variants of concern under in vitro neutralising selection pressure following two doses of the Pfizer-BioNTech BNT162b2 COVID-19 vaccine | bioRxiv Key Points This paper investigates the neutralizing antibody responses against different SARS-CoV-2 variants after vaccination with two doses of the Pfizer-BioNTech COVID-19 vaccine. Here are the key findings: Serum samples were collected from 14 participants, including 12 vaccinated with two doses of Pfizer's vaccine, median 21 days after the second dose. The sera were tested against three SARS-CoV-2 strains - wildtype, Beta variant, and Delta variant - using a live virus neutralization assay. Neutralizing antibody titers (nAbT) were significantly lower against Delta variant compared to wildtype, with a 4.4-fold reduction. nAbT against Beta variant were also reduced 2.3-fold versus wildtype. No neutralizing antibodies were detected in the two unvaccinated participants, nor in one immunosuppressed

Polyphyllin I is a natural compound found in various plants, particularly in species of the genus Paris, which belongs to the family Melanthiaceae. These plants are commonly known as "true Paris" or "herb Paris." Polyphyllin I is classified as a steroidal saponin, which means it is a type of glycoside compound with a steroidal nucleus. Steroidal saponins like Polyphyllin I have been of interest in the field of pharmacology and traditional medicine due to their potential therapeutic properties. Polyphyllin I and related compounds have been investigated for various biological activities, including their potential as anticancer agents. Research has suggested that Polyphyllin I may have cytotoxic (cell-killing) effects on certain cancer cells, making it a subject of interest in cancer research. Additionally, it has been studied for its potential anti-inflammatory and immunomodulatory properties. It's important to note that while there is some scienti

Polyphyllin I induces cell cycle arrest in prostate cancer c... : Medicine journals.lww.com Polyphyllin I induces cell cycle arrest in prostate cancer... : Medicine Author Information 20–26 minutes 1 Introduction Prostate cancer is one of the most common causes of cancer-related mortality in men. [1,2] Despite advances in early diagnosis and treatment, prostate cancer morbidity remains high. The survival rates remain poor, especially among castration-resistant prostate cancer patients, [3,4] although chemotherapy has significantly improved the prognosis of prostate cancer patients. Additionally, the severe systemic toxicity of chemotherapeutic drugs has limited the application of these drugs. Moreover, patients have compromised quality of life (due to the high side effects) and pay high costs for treatment, especially in developing countries. Therefore, the development of

Ferroptosis landscape in prostate cancer from molecular and metabolic perspective | Cell Death Discovery nature.com Ferroptosis landscape in prostate cancer from molecular and metabolic perspective Jiang, Ning 89–113 minutes Review Article Open Access Published: 15 April 2023 Yihao Liao 1   na1 , Pu Wang 1   na1 , Kun Yang 2 , Youzhi Wang 1 , Keke Wang 3 , Boqiang Zhong 1 , Diansheng Zhou 1 , Qian Cao 1 , Junbo Li 1 , Yang Zhao 4 &… Ning Jiang   ORCID: orcid.org/0000-0002-9851-0863 1   Cell Death Discovery volume  9 , Article number:  128 ( 2023 )