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Showing posts from November, 2021

After Doc Uproar, NCCN Reverses Prostate Cancer Guidance

After Doc Uproar, NCCN Reverses Prostate Cancer Guidance : The cancer organization today largely reinstated its former advice that men with low-risk prostate cancer be offered active surveillance as the lone 'preferred' initial treatment option.

Statin use affects prostate cancer screening results -- ScienceDaily

Statin use affects prostate cancer screening results -- ScienceDaily

Projected attendance at AS research conference | THE "NEW" PROSTATE CANCER INFOLINK

Projected attendance at AS research conference | THE "NEW" PROSTATE CANCER INFOLINK

Combination therapy with novel androgen receptor antagonists and statin for castration‐resistant prostate cancer - Nakayama - - The Prostate - Wiley Online Library

Combination therapy with novel androgen receptor antagonists and statin for castration‐resistant prostate cancer - Nakayama - - The Prostate - Wiley Online Library

Is tumour volume an independent predictor of outcome after radical prostatectomy for high-risk prostate cancer? | Prostate Cancer and Prostatic Diseases

Is tumour volume an independent predictor of outcome after radical prostatectomy for high-risk prostate cancer? | Prostate Cancer and Prostatic Diseases

Preparing for Cancer Treatment and Life Afterwards | Cancer Research UK - YouTube

Preparing for Cancer Treatment and Life Afterwards | Cancer Research UK - YouTube

Effects of the 2012 and 2018 US preventive services task force prostate cancer screening guidelines on pathologic outcomes after prostatectomy - Plambeck - - The Prostate - Wiley Online Library

Effects of the 2012 and 2018 US preventive services task force prostate cancer screening guidelines on pathologic outcomes after prostatectomy - Plambeck - - The Prostate - Wiley Online Library

Effects of yoga in men with prostate cancer on quality of life and immune response: a pilot randomized controlled trial | Prostate Cancer and Prostatic Diseases

Effects of yoga in men with prostate cancer on quality of life and immune response: a pilot randomized controlled trial | Prostate Cancer and Prostatic Diseases : Diagnosis and treatment of prostate cancer is associated with anxiety, fear, and depression in up to one-third of men. Yoga improves health-related quality of life (QoL) in patients with several types of cancer, but evidence of its efficacy in enhancing QoL is lacking in prostate cancer. In this randomized controlled study, 29 men newly diagnosed with localized prostate cancer were randomized to yoga for 6 weeks (n = 14) or standard-of-care (n = 15) before radical prostatectomy. The primary outcome was self-reported QoL, assessed by the Expanded Prostate Index Composite (EPIC), Functional Assessment of Cancer Therapy-Prostate (FACT-P), Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT–F), Functional Assessment of Cancer Therapy-General (FACT-G) at baseline, preoperatively, and 6 weeks postoperatively. Secondary

Improved survival with post-diagnostic metformin and statin use in a racially diverse cohort of US Veterans with advanced prostate cancer | Prostate Cancer and Prostatic Diseases

Improved survival with post-diagnostic metformin and statin use in a racially diverse cohort of US Veterans with advanced prostate cancer | Prostate Cancer and Prostatic Diseases

Androgen deprivation therapy and acute kidney injury in patients with prostate cancer undergoing definitive radiotherapy | Prostate Cancer and Prostatic Diseases

Androgen deprivation therapy and acute kidney injury in patients with prostate cancer undergoing definitive radiotherapy | Prostate Cancer and Prostatic Diseases

Selective Intra-Arterial 177Lu-PSMA Therapy for Castration Resistant Prostate Cancer: Initial Results - ScienceDirect

Selective Intra-Arterial 177Lu-PSMA Therapy for Castration Resistant Prostate Cancer: Initial Results - ScienceDirect

Gene expression based inference of drug resistance in cancer | bioRxiv

Gene expression based inference of drug resistance in cancer | bioRxiv

Year in Review: Prostate Cancer | MedPage Today

Year in Review: Prostate Cancer | MedPage Today

A Q&A With Thomas Hope, MD on PSMA PET Imaging for Prostate Cancer | UCSF Radiology

A Q&A With Thomas Hope, MD on PSMA PET Imaging for Prostate Cancer | UCSF Radiology

The prostate cancer cell that got away -- ScienceDaily

The prostate cancer cell that got away -- ScienceDaily

Association of Short-term Patient-reported Outcomes with Long-term Oncologic Outcomes in Localized Prostate Cancer Patients Treated with Radiotherapy and ADT in a Randomized Controlled Trial - International Journal of Radiation Oncology, Biology, Physics

Association of Short-term Patient-reported Outcomes with Long-term Oncologic Outcomes in Localized Prostate Cancer Patients Treated with Radiotherapy and ADT in a Randomized Controlled Trial - International Journal of Radiation Oncology, Biology, Physics

Disparities in germline testing among racial minorities with prostate cancer | Prostate Cancer and Prostatic Diseases

Disparities in germline testing among racial minorities with prostate cancer | Prostate Cancer and Prostatic Diseases

PFAS exposure, high-fat diet drive prostate cells’ metabolism into pro-cancer state: Dietary fat synergizes with PFAS to trigger cancer in benign cells, accelerate tumor growth in malignant cells -- ScienceDaily

PFAS exposure, high-fat diet drive prostate cells’ metabolism into pro-cancer state: Dietary fat synergizes with PFAS to trigger cancer in benign cells, accelerate tumor growth in malignant cells -- ScienceDaily

Long‐term first‐in‐man Phase I/II study of an adjuvant dendritic cell vaccine in patients with high‐risk prostate cancer after radical prostatectomy - Tryggestad - - The Prostate - Wiley Online Library

Long‐term first‐in‐man Phase I/II study of an adjuvant dendritic cell vaccine in patients with high‐risk prostate cancer after radical prostatectomy - Tryggestad - - The Prostate - Wiley Online Library

Registration for major active surveillance (AS) research conference now open | THE "NEW" PROSTATE CANCER INFOLINK

Registration for major active surveillance (AS) research conference now open | THE "NEW" PROSTATE CANCER INFOLINK

Shock, Disbelief as NCCN Changes Prostate Cancer Guidance

Shock, Disbelief as NCCN Changes Prostate Cancer Guidance

Virtual Prostate Cancer Clinic: Thumbs Up From Patients and Docs

Virtual Prostate Cancer Clinic: Thumbs Up From Patients and Docs : The majority of patients were comfortable with being monitored in this way, and it saved them time and money while freeing up clinicians to accept new patients.

Five Percent Overall Medicare Reimbursement Cut Estimated for Medical Oncology in 2022 | ASCO

Five Percent Overall Medicare Reimbursement Cut Estimated for Medical Oncology in 2022 | ASCO

The Paradox of a Man’s Most-Feared Test, the PSA | The MIT Press Reader

The Paradox of a Man’s Most-Feared Test, the PSA | The MIT Press Reader

Vitamin D deficiency increases prostatic megalin expression and globulin-bound testosterone import, increasing prostatic androgens in African American men | bioRxiv

Vitamin D deficiency increases prostatic megalin expression and globulin-bound testosterone import, increasing prostatic androgens in African American men | bioRxiv

Are the Right Men Getting Screened for Prostate Cancer? | MedPage Today

Are the Right Men Getting Screened for Prostate Cancer? | MedPage Today

Urine Test for Prostate Cancer Signals Amount of Aggressive Tumor

Urine Test for Prostate Cancer Signals Amount of Aggressive Tumor

Modeling the mechanisms of metastasis | MIT News | Massachusetts Institute of Technology

Modeling the mechanisms of metastasis | MIT News | Massachusetts Institute of Technology

Stereotactic Ablative Radiotherapy for High-Risk Prostate Cancer—a Prospective Multi-level MRI-based Dose Escalation Trial - International Journal of Radiation Oncology, Biology, Physics

Stereotactic Ablative Radiotherapy for High-Risk Prostate Cancer—a Prospective Multi-level MRI-based Dose Escalation Trial - International Journal of Radiation Oncology, Biology, Physics

A rare insight into the immunosuppressive landscape of prostate cancer bone metastases: Cancer Cell

A rare insight into the immunosuppressive landscape of prostate cancer bone metastases: Cancer Cell

New strategy against treatment-resistant prostate cancer identified: RNA molecule suppresses prostate tumor growth -- ScienceDaily

New strategy against treatment-resistant prostate cancer identified: RNA molecule suppresses prostate tumor growth -- ScienceDaily

Urine Test May Spot Aggressive Prostate Cancer

Urine Test May Spot Aggressive Prostate Cancer

Five Percent Overall Medicare Reimbursement Cut Estimated for Medical Oncology in 2022 | ASCO

Five Percent Overall Medicare Reimbursement Cut Estimated for Medical Oncology in 2022 | ASCO

Cleveland Clinic Study Links Gut Microbiome and Aggressive Prostate Cancer – Cleveland Clinic Newsroom

Cleveland Clinic Study Links Gut Microbiome and Aggressive Prostate Cancer – Cleveland Clinic Newsroom

Prostate cancer research in the 21st century; report from the 2021 Coffey‐Holden prostate cancer academy meeting - Miyahira - - The Prostate - Wiley Online Library

Prostate cancer research in the 21st century; report from the 2021 Coffey‐Holden prostate cancer academy meeting - Miyahira - - The Prostate - Wiley Online Library

Is Collecting Long-term Cancer Follow-up Data Worth It?

Is Collecting Long-term Cancer Follow-up Data Worth It?

Survival by race in men with chemotherapy-naive enzalutamide- or abiraterone-treated metastatic castration-resistant prostate cancer | Prostate Cancer and Prostatic Diseases

Survival by race in men with chemotherapy-naive enzalutamide- or abiraterone-treated metastatic castration-resistant prostate cancer | Prostate Cancer and Prostatic Diseases

Salvage Low Dose Rate Prostate Brachytherapy: Clinical Outcomes of a Phase II Trial for Local Recurrence after External Beam Radiotherapy (NRG Oncology/xxxx) - ScienceDirect

Salvage Low Dose Rate Prostate Brachytherapy: Clinical Outcomes of a Phase II Trial for Local Recurrence after External Beam Radiotherapy (NRG Oncology/xxxx) - ScienceDirect

Estimating patient health in prostate cancer treatment counseling | Prostate Cancer and Prostatic Diseases

Estimating patient health in prostate cancer treatment counseling | Prostate Cancer and Prostatic Diseases

Prostate cancer urine test identifies good prognosis patients -- ScienceDaily

Prostate cancer urine test identifies good prognosis patients -- ScienceDaily

Survival by race in men with chemotherapy-naive enzalutamide- or abiraterone-treated metastatic castration-resistant prostate cancer | Prostate Cancer and Prostatic Diseases

Survival by race in men with chemotherapy-naive enzalutamide- or abiraterone-treated metastatic castration-resistant prostate cancer | Prostate Cancer and Prostatic Diseases

Time for Targeted PSA Screening for Men With Rare Pathogenic Variants? | MedPage Today

Time for Targeted PSA Screening for Men With Rare Pathogenic Variants? | MedPage Today

Patient-reported outcomes in the acute phase of the randomized hypofractionated irradiation for prostate cancer (HYPRO) trial - International Journal of Radiation Oncology, Biology, Physics

Patient-reported outcomes in the acute phase of the randomized hypofractionated irradiation for prostate cancer (HYPRO) trial - International Journal of Radiation Oncology, Biology, Physics

Salvage Low Dose Rate Prostate Brachytherapy: Clinical Outcomes of a Phase II Trial for Local Recurrence after External Beam Radiotherapy (NRG Oncology/xxxx) - International Journal of Radiation Oncology, Biology, Physics

Salvage Low Dose Rate Prostate Brachytherapy: Clinical Outcomes of a Phase II Trial for Local Recurrence after External Beam Radiotherapy (NRG Oncology/xxxx) - International Journal of Radiation Oncology, Biology, Physics

Active Surveillance: The Sweet Smell of Success - YouTube

Active Surveillance: The Sweet Smell of Success - YouTube Top Swedish urologist Ola Bratt, MD, the speaker at the ASPI webinar on Oct. 30, a consultant urological surgeon at the Prostate Cancer Centre, Sahlgrenska University Hospital Gothenburg, Sweden, said research is clear that men can co-exist with Gleason 6 cancers because they  are indolent and virtually never metastasize or spread. He stresses that these cancer cells are not dangerous. Dr. Bratt, chairman of the Swedish National Prostate Cancer Guidelines Group and who also chairs the committee preparing for a national screening program for prostate cancer, has developed over the years a kinder, gentler way to break the news. He said he tells them: “You have no cancer that needs to be treated.” That statement takes the shock out of the diagnosis. So active surveillance, close monitoring of the cancer, has been a hit in Sweden among men with very low-risk disease. More than 90% of Swedish men in this situation opt for

Reversal of lineage plasticity in RB1/TP53-deleted prostate cancer through FGFR and Janus kinase inhibition | bioRxiv

Reversal of lineage plasticity in RB1/TP53-deleted prostate cancer through FGFR and Janus kinase inhibition | bioRxiv

High-Intensity Interval Training in Prostate Cancer | JAMA | JAMA Network

High-Intensity Interval Training in Prostate Cancer | JAMA | JAMA Network

HYPORT in Prostate Cancer: New Standard After Surgery?

HYPORT in Prostate Cancer: New Standard After Surgery?

Biomarkers Associating with PARP Inhibitor Benefit in Prostate Cancer in the TOPARP-B Trial | Cancer Discovery

Biomarkers Associating with PARP Inhibitor Benefit in Prostate Cancer in the TOPARP-B Trial | Cancer Discovery

GRPr Antagonist 68Ga-SB3 PET/CT Imaging of Primary Prostate Cancer in Therapy-Naïve Patients | Journal of Nuclear Medicine

GRPr Antagonist 68Ga-SB3 PET/CT Imaging of Primary Prostate Cancer in Therapy-Naïve Patients | Journal of Nuclear Medicine

Early Injection of Furosemide Increases Detection Rate of Local Recurrence in Prostate Cancer Patients with Biochemical Recurrence Referred for 68Ga-PSMA-11 PET/CT | Journal of Nuclear Medicine

Early Injection of Furosemide Increases Detection Rate of Local Recurrence in Prostate Cancer Patients with Biochemical Recurrence Referred for 68Ga-PSMA-11 PET/CT | Journal of Nuclear Medicine : The aim of this study was twofold. First, we aimed to assess the impact of forced diuresis with early furosemide injection on the detection rate of local recurrence in prostate cancer patients with biochemical recurrence referred for 68Ga-labeled Glu-NH-CO-NH-Lys(Ahx)-HBED-CC (68Ga-PSMA-11) PET/CT. Second, we determined whether intravenous administration of furosemide shortly after tracer injection increases renal washout of 68Ga-PSMA-11 before it binds to the PSMA receptor with possible influence on biodistribution and intensity of tracer uptake in organs with physiologic tracer accumulation. Methods: In a retrospective analysis, 2 different groups with 220 prostate cancer patients each, referred for 68Ga-PSMA-11 PET/CT because of biochemical recurrence after primary therapy, were compared: p

PSMA- and GRPR-Targeted PET: Results from 50 Patients with Biochemically Recurrent Prostate Cancer | Journal of Nuclear Medicine

PSMA- and GRPR-Targeted PET: Results from 50 Patients with Biochemically Recurrent Prostate Cancer | Journal of Nuclear Medicine