What to Expect and Plan for in Pluvicto Treatment:
What to Expect and Plan for in Pluvicto Treatment: A Comprehensive Guide for Prostate Cancer Patients Special Report for the IPCSG Newsletter Major FDA Expansion Opens Treatment to More Patients On March 28, 2025, the FDA expanded approval for Pluvicto (lutetium Lu 177 vipivotide tetraxetan) to include patients with PSMA-positive metastatic castration-resistant prostate cancer (mCRPC) who have been treated with androgen receptor pathway inhibitor (ARPI) therapy and are considered appropriate to delay chemotherapy. This expanded indication approximately triples the number of patients eligible to receive Pluvicto. This groundbreaking development means that many more patients can now access this innovative treatment earlier in their disease progression, potentially before requiring chemotherapy. Understanding Pluvicto: How It Works Pluvicto is a "theranostic" medicine that combines diagnostic and therapeutic capabilities. It's a type of radiation that specif...