Mathematical Modeling Shows Promise for Personalizing Lutetium-177 PSMA Therapy in Advanced Prostate Cancer
Understanding the Mathematical Model: A Visual Guide This diagram shows how researchers created a computer model to simulate what happens in your body during Lutetium-177 PSMA therapy. Let me break it down into understandable parts: The Left Side: What Happens to Cancer Cells The green, orange, and red cells represent different states of prostate cancer cells in your body: Green cells (MTP) - These are actively growing cancer cells They multiply at a rate called "kg" (growth rate) Some can repair themselves (shown by the curved arrow with "μT") Orange cells (MTSD) - These are damaged but not yet dead Cancer cells hit by radiation but not killed immediately They might repair and turn back into green cells, OR They might get hit again and die Red cells (MTD) - These are lethally damaged, dying cells Cancer cells that have been fatally damaged by radiation They get cleared away from your body at rate "kc" The yellow lightning bolt (AT) represent...