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Tumor-Derived Extracellular Vesicles Predict Clinical Outcomes in Oligometastatic Prostate Cancer and Suppress Antitumor Immunity - ScienceDirect sciencedirect.com Tumor-Derived Extracellular Vesicles Predict Clinical Outcomes in Oligometastatic Prostate Cancer and Suppress Antitumor Immunity 3 minutes Access through  your institution Outline Abstract Introduction Materials and Methods Results Discussion Conclusions References Appendix. Supplementary materials Figures (6) Abstract Purpose Stereotactic ablative radiotherapy (SABR) has demonstrated clinical benefit in oligometastatic prostate cancer. However, the risk of developing new distant metastatic lesions remains high and only a minority of patients experience durable progression-free response. Therefore, there is a critical need to identify which patients will benefit from SABR alone versus combination SABR and systemic agents....

Para-Aortic Radiation Therapy for Oligorecurrent Prostate Cancer - ScienceDirect sciencedirect.com Para-Aortic Radiation Therapy for Oligorecurrent Prostate Cancer 3 minutes Access through  your institution Outline ABSTRACT Keywords INTRODUCTION MATERIALS AND METHODS RESULTS DISCUSSION CONCLUSIONS REFERENCES Appendix. Supplementary materials Figures (4) ABSTRACT Purpose: Oligorecurrent prostate cancer limited to the pelvic lymph nodes (LNs) can be treated with whole pelvis radiotherapy. Radiotherapy may also be beneficial for oligorecurrent prostate cancer in the para-aortic (PA) LNs. Methods: We identified a sequential cohort of patients with oligorecurrent prostate cancer to the PA LNs (≤5) treated with elective, conventionally fractionated PA radiotherapy (PA-RT) plus simultaneous integrated boost (SIB) to LN+ disease at our institution from 2015 to 2021. The primary endpoint wa...

Salvage Prostate Stereotactic Body Radiation Therapy After Definitive Cryoablation - Docwire News   docwirenews.com Salvage Prostate Stereotactic Body Radiation Therapy After Definitive Cryoablation 3 minutes This article was originally published here Adv Radiat Oncol. 2021 Nov 13;7(3):100849. doi: 10.1016/j.adro.2021.100849. eCollection 2022 May-Jun. ABSTRACT PURPOSE: Whole gland cryoablation is a guideline-approved definitive treatment for localized prostate cancer, and is being explored for partial gland ablation. However, there is limited data regarding management of cryoablation failures. Stereotactic body radiation therapy (SBRT) is a well-established method of primary treatment for prostate cancer. Here we review salvage SBRT after cryoablation failures. METHODS AND MATERIALS: A large database of patients treated with definitive SBRT was interrogated to identify those who und...

Finding Hidden Cancer Cells: FDA Approval of New Imaging Tool Could Transform Treatment Decisions for Advanced Prostate Cancer | Memorial Sloan Kettering Cancer Center

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Metastasis-free survival and patterns of distant metastatic disease after PSMA-PET-guided salvage radiotherapy in recurrent or persistent prostate cancer after prostatectomy - International Journal of Radiation Oncology, Biology, Physics redjournal.org Metastasis-free survival and patterns of distant metastatic disease after PSMA-PET-guided salvage radiotherapy in recurrent or persistent prostate cancer after prostatectomy Search for articles by this author 6-7 minutes Abstract Introduction: Prostate specific membrane antigen positron-emission tomography (PSMA-PET) is increasingly used to guide salvage radiotherapy (sRT) in prostate cancer (PCa) patients with biochemical recurrence/persistence after prostatectomy. This work examines (i) metastasis-free survival (MFS) following PSMA-PET guided sRT and (ii) the metastatic patterns on PSMA-PET i...

Rates of metastatic prostate cancer in newly diagnosed patients: Numbers needed to image according to risk level - Sorce - - The Prostate - Wiley Online Library